Yes, Power BI is designed to handle large datasets efficiently through its advanced data modeling capabilities and DirectQuery feature, which allows real-time access to data sources. However, to ensure optimal performance, it is crucial to configure data models properly. Power BI development experts play a vital role in optimizing datasets, reducing query time, and maintaining system efficiency, especially in large-scale enterprise environments. They implement best practices to prevent data overload, ensuring that users get fast and accurate insights without performance issues.